Topical application of Hydroquinone produces a reversible depigmentation of the skin by inhibition of the enzymatic oxidation of tyrosine to 3, 4-dihydroxyophenyl alanine (dopa) and suppression of other melanocyte metabolic processes.

For the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other unwanted areas of melanin hyperpigmentation.

Hydroquinone should not be applied to abraded or sunburnt skin. It should not be used to bleach eyelashes or eyebrows and contact with the eyes should be avoided as it may produce staining and corneal opacities. High concentrations or prolonged use may produce hyperpigmentation especially on areas of skin exposed to sunlight.

None.

No systemic adverse reactions have been reported. Occasional hypersensitivity (localized contact dermatitis) may occur.

Hydroquinone should be applied twice daily only to intact skin which should be protected from sunlight to reduce repigmentation.